TDP2 Antikörper (Middle Region)

Produktnummer ABIN2777707

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-TDP2 Antikörper wird verwendet zum Nachweis von TDP2 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd und Meerschweinchen. Er wurde validiert für WB und IHC.

Kurzübersicht für TDP2 Antikörper (Middle Region) (ABIN2777707)

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TDP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IPPYYSYLKK RSSNYEIITG HEEGYFTAIM LKKSRVKLKS QEIIPFPSTK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TTRAP. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TTRAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 362 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TDP2 Antikörper (ABIN2777707)

Xu, Pan, Wang, Huang, Tian, Xue, Chen, Jia: "TTRAP is a novel PML nuclear bodies-associated protein." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 395-8, (2008) (PubMed).

Details zu TDP2

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Andere Bezeichnung: TTRAP

Hintergrund: The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Alias Symbols: TDP2, EAP2, AD022, EAPII, TTRAP, dJ30M3.3, RP1-30M3.3
Protein Interaction Partner: UBC, SRPK2, SUMO1, SUMO2, SUMO3, TAP1, SKIL, ATXN1, PSEN1, SMAD3, EPS8, DLX3, ATP5G2, C2orf88, JAM2, SNX13, AKAP9, RAB11A, PARK7, MAPK6, UBE2I, TRAF5, TRAF6, TRAF3, TRAF2, FLI1, TNFRSF1B, ETS2, ETS1, TNFRSF8, CD40, HTNVsSgp1,
Protein Size: 362

Molekulargewicht: 41 kDa

Gen-ID: 51567

NCBI Accession: NM_016614, NP_057698

UniProt: O95551