TDP2 Antikörper (Middle Region)

Produktnummer ABIN2777707

Der Kaninchen Polyklonal Anti-TDP2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, TDP2 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd und Meerschweinchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für TDP2 Antikörper (Middle Region) (ABIN2777707)

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TDP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IPPYYSYLKK RSSNYEIITG HEEGYFTAIM LKKSRVKLKS QEIIPFPSTK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TTRAP. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TTRAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 362 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TDP2 Antikörper (ABIN2777707)

Xu, Pan, Wang, Huang, Tian, Xue, Chen, Jia: "TTRAP is a novel PML nuclear bodies-associated protein." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 395-8, (2008) (PubMed).

Details zu TDP2

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Andere Bezeichnung: TTRAP

Hintergrund: The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Alias Symbols: TDP2, EAP2, AD022, EAPII, TTRAP, dJ30M3.3, RP1-30M3.3
Protein Interaction Partner: UBC, SRPK2, SUMO1, SUMO2, SUMO3, TAP1, SKIL, ATXN1, PSEN1, SMAD3, EPS8, DLX3, ATP5G2, C2orf88, JAM2, SNX13, AKAP9, RAB11A, PARK7, MAPK6, UBE2I, TRAF5, TRAF6, TRAF3, TRAF2, FLI1, TNFRSF1B, ETS2, ETS1, TNFRSF8, CD40, HTNVsSgp1,
Protein Size: 362

Molekulargewicht: 41 kDa

Gen-ID: 51567

NCBI Accession: NM_016614, NP_057698

UniProt: O95551