HNF1B Antikörper (N-Term)

Produktnummer ABIN2777700

Dieses Anti-HNF1B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HNF1B in WB. Geeignet für Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Meerschweinchen und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für HNF1B Antikörper (N-Term) (ABIN2777700)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HNF1B Antikörper

Bindungsspezifität: N-Term

Sequenz: NFGVKLETLP LSPGSGAEPD TKPVFHTLTN GHAKGRLSGD EGSEDGDDYD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 92%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 557 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNF1B Antikörper (ABIN2777700)

Hakonarson, Qu, Bradfield, Marchand, Kim, Glessner, Grabs, Casalunovo, Taback, Frackelton, Eckert, Annaiah, Lawson, Otieno, Santa, Shaner, Smith, Onyiah, Skraban, Chiavacci, Robinson, Stanley, Kirsch et al.: "A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. ..." in: Diabetes, Vol. 57, Issue 4, pp. 1143-6, (2008) (PubMed).

Details zu HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Andere Bezeichnung: HNF1B

Hintergrund: HNF1B is a member of the transcription factor superfamily. It forms heterodimers with another member of this transcription factor family, HNF1A. Multiple alternatively spliced transcript variants have been described, however the biological validity all of these variants needs to be determined.This gene encodes a member of the transcription factor superfamily. The encoded protein forms heterodimers with another member of this transcription factor family, HNF1A. Multiple alternatively spliced transcript variants have been described, however the biological validity all of these variants needs to be determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-473 DC340648.1 1-473 474-1994 BC017714.1 441-1961 1995-2544 AC091199.6 29528-30077 2545-2842 AI797324.1 1-298 c
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
Protein Size: 557

Molekulargewicht: 61 kDa

Gen-ID: 6928

NCBI Accession: NM_000458, NP_000449

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation