REXO4 Antikörper (Middle Region)

Produktnummer ABIN2777670

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch REXO4 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für REXO4 Antikörper (Middle Region) (ABIN2777670)

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-REXO4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PADIEAAIGP EAAKIARKQL GQSEGSVSLS LVKEQAFGGL TRALALDCEM

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human REXO4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-REXO4 Antikörper (ABIN2777670)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu REXO4

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Andere Bezeichnung: REXO4

Hintergrund: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: XPMC2, XPMC2H, REX4
Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
Protein Size: 422

Molekulargewicht: 47 kDa

Gen-ID: 57109

NCBI Accession: NM_020385, NP_065118

UniProt: Q9GZR2