Hairless Antikörper (Middle Region)

Produktnummer ABIN2777657

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Hairless in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für Hairless Antikörper (Middle Region) (ABIN2777657)

Target: Hairless (HR)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hairless Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Hairless Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: HR Antibody - middle region

Sequenz: RVWAPGDAGQ QKESTQKTPP TPQPSCNGDT HRTKSIKEET PDSAETPAED

Homologie: Cow: 77%, Dog: 85%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against HR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32907-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Hairless

Target: Hairless (HR)

Andere Bezeichnung: HR

Hintergrund:

Background Information: HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Hairless homolog (mouse)

Alternative Symbols: AU, MUHH, ALUNC, HYPT4, MUHH1, HSA277165

Protein Name: Protein hairless

Molekulargewicht: 127kDa

Gen-ID: 55806

NCBI Accession: NP_005135

UniProt: O43593