HES6 Antikörper (Middle Region)

Produktnummer ABIN2777652

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HES6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für HES6 Antikörper (Middle Region) (ABIN2777652)

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HES6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HES6 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Hes6 Antibody - middle region

Sequenz: LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against Hes6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hes6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32897-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HES6

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Andere Bezeichnung: Hes6

Hintergrund:

Background Information: Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation.

Alternative Symbols: bHLHb4, bHLHb41, AI326893

Protein Name: Transcription cofactor HES-6

Molekulargewicht: 24kDa

Gen-ID: 55927

NCBI Accession: NP_062352

UniProt: Q9JHE6