Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) Antikörper

Produktnummer ABIN2777593

Der Kaninchen Polyklonal anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial Antikörper wird verwendet zum Nachweis von Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial in Proben von Human, Maus, Ratte, Rind (Kuh) und Pferd. Er wurde validiert für WB.

Kurzübersicht für Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) Antikörper (ABIN2777593)

Target: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Sequenz: AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT

Homologie: Cow: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against ACADM. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

Andere Bezeichnung: ACADM

Hintergrund: ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ACAD1, MCAD, MCADH
Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, STRAP, HDAC1, UBD, CUL3, SUMO4, CALM1, USP50, USP20, ACADM,
Protein Size: 421

Molekulargewicht: 46 kDa

Gen-ID: 34

NCBI Accession: NM_000016, NP_000007

UniProt: P11310