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ACSL1 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ACSL1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2777590

Kurzübersicht für ACSL1 Antikörper (C-Term) (ABIN2777590)

Target

Alle ACSL1 (Acsl1) Antikörper anzeigen
ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reaktivität

  • 27
  • 11
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio)

Wirt

  • 28
  • 1
Kaninchen

Klonalität

  • 28
  • 1
Polyklonal

Konjugat

  • 22
  • 3
  • 1
  • 1
  • 1
  • 1
Dieser ACSL1 Antikörper ist unkonjugiert

Applikation

  • 24
  • 15
  • 8
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    GSFEELCRNK DVKKAILEDM VRLGKDSGLK PFEQVKGITL HPELFSIDNG

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human ACSL1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 698 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Golej, Askari, Kramer, Barnhart, Vivekanandan-Giri, Pennathur, Bornfeldt: "Long-chain acyl-CoA synthetase 4 modulates prostaglandin E? release from human arterial smooth muscle cells." in: Journal of lipid research, Vol. 52, Issue 4, pp. 782-93, (2011) (PubMed).

  • Target

    ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

    Andere Bezeichnung

    ACSL1

    Hintergrund

    ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
    Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
    Protein Size: 698

    Molekulargewicht

    78 kDa

    Gen-ID

    2180

    NCBI Accession

    NM_001995, NP_001986

    UniProt

    P33121

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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