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MXD4 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MXD4 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Schaf.
Produktnummer ABIN2777585

Kurzübersicht für MXD4 Antikörper (N-Term) (ABIN2777585)

Target

Alle MXD4 Antikörper anzeigen
MXD4 (MAX Dimerization Protein 4 (MXD4))

Reaktivität

Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Schaf

Wirt

  • 14
  • 3
  • 1
Kaninchen

Klonalität

  • 17
  • 1
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MXD4 Antikörper ist unkonjugiert

Applikation

  • 7
  • 6
  • 5
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    SLLILLEAAE YLERRDREAE HGYASVLPFD GDFAREKTKA AGLVRKAPNN

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Sheep: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against MXD4. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 209 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    MXD4 (MAX Dimerization Protein 4 (MXD4))

    Andere Bezeichnung

    MXD4

    Hintergrund

    MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
    Alias Symbols: MAD4, MST149, MSTP149, bHLHc12
    Protein Interaction Partner: TCP10L, UBC, SHBG, SIN3A, MLX, MAX, SMC3,
    Protein Size: 209

    Molekulargewicht

    24 kDa

    Gen-ID

    10608

    NCBI Accession

    NM_006454, NP_006445

    UniProt

    Q14582
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