T-Box 22 Antikörper (Middle Region)

Produktnummer ABIN2777562

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch T-Box 22 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein und Kaninchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für T-Box 22 Antikörper (Middle Region) (ABIN2777562)

Target: T-Box 22 (TBX22)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-T-Box 22 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TBX22 Antibody - middle region

Sequenz: QSMHKYKPRV HVIEQGSSVD LSQIQSLPTE GVKTFSFKET EFTTVTAYQN

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TBX22. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX22

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32745-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-T-Box 22 Antikörper (ABIN2777562)

Suphapeetiporn, Tongkobpetch, Siriwan, Shotelersuk: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).

Details zu T-Box 22

Target: T-Box 22 (TBX22)

Andere Bezeichnung: TBX22

Hintergrund:

Background Information: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: T-box 22

Alternative Symbols: CPX, CLPA, TBXX, ABERS, dJ795G23.1

Protein Name: T-box transcription factor TBX22

Molekulargewicht: 58kDa

Gen-ID: 50945

NCBI Accession: NP_058650

UniProt: Q9Y458