MAP4K6 Antikörper (Middle Region)

Produktnummer ABIN2777554

Produktdetails anti-MAP4K6 Antikörper

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PDSSPVLSPG NKAKPDDHRS RPGRPADFVL LKERTLDEAP RPPKKAMDYS

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MINK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MINK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1312 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP4K6

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Andere Bezeichnung: MINK1 (MINK1 Produkte)

Synonyme: MINK1 antikoerper, MINK antikoerper, B55 antikoerper, MAP4K6 antikoerper, YSK2 antikoerper, ZC3 antikoerper, hMINK antikoerper, hMINKbeta antikoerper, MEKKK 6 antikoerper, Map4k6 antikoerper, RP23-122P1.6 antikoerper, Ysk2 antikoerper, misshapen like kinase 1 antikoerper, misshapen-like kinase 1 antikoerper, misshapen-like kinase 1 (zebrafish) antikoerper, MINK1 antikoerper, Mink1 antikoerper

Hintergrund: MINK1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
Alias Symbols: B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK, hMINKbeta
Protein Interaction Partner: UBC, HSP90AA1, NEDD4L, CASKIN1, SPTBN2, PKP4, ABI1, TUBA1B, KIFAP3, YWHAB, YWHAZ, NCK1, NEFM, MAP1B, CALM3, ACTA2,
Protein Size: 1312

Molekulargewicht: 148 kDa

Gen-ID: 50488

NCBI Accession: NM_001024937, NP_001020108

UniProt: Q5U8Z0

Pathways: Synaptic Membrane