MAP4K6 Antikörper (Middle Region)

Produktnummer ABIN2777554

Dieser Anti-MAP4K6 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MAP4K6 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Hund, Kaninchen und Meerschweinchen.

Kurzübersicht für MAP4K6 Antikörper (Middle Region) (ABIN2777554)

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP4K6 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PDSSPVLSPG NKAKPDDHRS RPGRPADFVL LKERTLDEAP RPPKKAMDYS

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MINK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MINK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1312 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP4K6

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Andere Bezeichnung: MINK1

Hintergrund: MINK1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
Alias Symbols: B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK, hMINKbeta
Protein Interaction Partner: UBC, HSP90AA1, NEDD4L, CASKIN1, SPTBN2, PKP4, ABI1, TUBA1B, KIFAP3, YWHAB, YWHAZ, NCK1, NEFM, MAP1B, CALM3, ACTA2,
Protein Size: 1312

Molekulargewicht: 148 kDa

Gen-ID: 50488

NCBI Accession: NM_001024937, NP_001020108

UniProt: Q5U8Z0

Pathways: Synaptic Membrane