HOXD3 Antikörper (Middle Region)

Produktnummer ABIN2777522

Der Kaninchen Polyklonal Anti-HOXD3-Antikörper wurde für WB validiert. Er ist geeignet, HOXD3 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für HOXD3 Antikörper (Middle Region) (ABIN2777522)

Target: HOXD3 (Homeobox D3 (HOXD3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXD3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AHKGAELNGS CMRPGTGNSQ GGGGGSQPPG LNSEQQPPQP PPPPPTLPPS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 432 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXD3 Antikörper (ABIN2777522)

Kodama, Sakai, Murakami, Murai, Mori, Maruo, Yanai, Masegi: "Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours." in: Journal of comparative pathology, Vol. 141, Issue 2-3, pp. 199-203, (2009) (PubMed).

Kodama, Sakai, Matsuura, Murakami, Murai, Mori, Maruo, Kimura, Masegi, Yanai: "Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes." in: BMC cancer, Vol. 9, pp. 363, (2009) (PubMed).

Details zu HOXD3

Target: HOXD3 (Homeobox D3 (HOXD3))

Andere Bezeichnung: HOXD3

Hintergrund: HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
Alias Symbols: HOX1D, HOX4, HOX4A, Hox-4.1, MGC10470
Protein Interaction Partner: Hoxa1, ALX4, DDB1, HMGB1,
Protein Size: 432

Molekulargewicht: 46 kDa

Gen-ID: 3232

NCBI Accession: NM_006898, NP_008829

UniProt: P31249