HOXA13 Antikörper (Middle Region)

Produktnummer ABIN2777518

Der Kaninchen Polyklonal Anti-HOXA13-Antikörper wurde für WB validiert. Er ist geeignet, HOXA13 in Proben von Human, Maus und Hund zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HOXA13 Antikörper (Middle Region) (ABIN2777518)

Target: HOXA13 (Homeobox A13 (HOXA13))

Reaktivität: Human, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXA13 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AAAAANQCRN LMAHPAPLAP GAASAYSSAP GEAPPSAAAA AAAAAAAAAA

Homologie: Dog: 83%, Human: 100%, Mouse: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXA13. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 388 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXA13 Antikörper (ABIN2777518)

Villavicencio-Lorini, Kuss, Friedrich, Haupt, Farooq, Türkmen, Duboule, Hecht, Mundlos: "Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation." in: The Journal of clinical investigation, Vol. 120, Issue 6, pp. 1994-2004, (2010) (PubMed).

Details zu HOXA13

Target: HOXA13 (Homeobox A13 (HOXA13))

Andere Bezeichnung: HOXA13

Hintergrund: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Alias Symbols: HOX1, HOX1J
Protein Interaction Partner: UBC, MEIS3, SMAD5, MEIS2, MEIS1, SMAD1, SMAD2,
Protein Size: 388

Molekulargewicht: 40 kDa

Gen-ID: 3209

NCBI Accession: NM_000522, NP_000513

UniProt: P31271