RACGAP1 Antikörper (N-Term)

Produktnummer ABIN2777488

Dieses Anti-RACGAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RACGAP1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für RACGAP1 Antikörper (N-Term) (ABIN2777488)

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RACGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RACGAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: EILSEGNEVQ FIQLAKDFED FRKKWQRTDH ELGKYKDLLM KAETERSALD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RACGAP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 632 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Andere Bezeichnung: RACGAP1

Hintergrund: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Alias Symbols: CYK4, ID-GAP, HsCYK-4, MgcRacGAP
Protein Interaction Partner: MORF4L1, UBC, FZR1, MPG, TXNDC11, MPRIP, TANK, KIF23, AURKB, PPP2R4, ECT2, CDK1, IKBKG, CUL1, SH3KBP1, Racgap1, Shcbp1, Cd2ap, YWHAG, YWHAB, PRC1, SH3RF1, SLC26A8, SLC16A10, PRSS23, CHN2, MAP3K4, RND2, MAP3K10, TUBG1, TUBA4A, VAV1, NRAS, GRB2, SFN,
Protein Size: 632

Molekulargewicht: 71 kDa

Gen-ID: 29127

NCBI Accession: NM_013277, NP_037409

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor