GFI1 Antikörper (N-Term)

Produktnummer ABIN2777468

Produktdetails anti-GFI1 Antikörper

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPRSFLVKSK KAHSYHQPRS PGPDYSLRLE NVPAPSRADS TSNAGGAKAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GFI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GFI1

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Andere Bezeichnung: GFI1 (GFI1 Produkte)

Synonyme: AW495828 antikoerper, Gfi-1 antikoerper, Pal-1 antikoerper, Pal1 antikoerper, GFI1 antikoerper, GFI-1 antikoerper, GFI1A antikoerper, SCN2 antikoerper, ZNF163 antikoerper, growth factor independent 1 antikoerper, growth factor independent 1 transcriptional repressor antikoerper, Gfi1 antikoerper, GFI1 antikoerper

Hintergrund: GFI1 may be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. GFI1 may be involved in tumor progression. Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) and dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA)
Alias Symbols: ZNF163, SCN2, GFI-1
Protein Interaction Partner: RELA, SPI1, CHAF1A, PICK1, PIAS2, RCOR1, KDM1A, HDAC2, PRDM5, HDAC1, EHMT2, PIAS3, RUNX1T1, ARIH2, UBC,
Protein Size: 422

Molekulargewicht: 46 kDa

Gen-ID: 2672

NCBI Accession: NM_005263, NP_005254

UniProt: Q99684