HEYL Antikörper (N-Term)

Produktnummer ABIN2777466

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HEYL in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund und Pferd und wurde in 1 Publikation erwähnt.

Kurzübersicht für HEYL Antikörper (N-Term) (ABIN2777466)

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEYL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HEYL Antikörper

Bindungsspezifität: N-Term

Sequenz: MKRPKEPSGS DGESDGPIDV GQEGQLSQMA RPLSTPSSSQ MQARKKRRGI

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HEYL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HEYL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 328 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HEYL Antikörper (ABIN2777466)

Morrow, Cullen, Liu, Guha, Sweeney, Birney, Collins, Walls, Redmond, Cahill: "Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 7, pp. 1112-8, (2009) (PubMed).

Details zu HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Andere Bezeichnung: HEYL

Hintergrund: HEYL belongs to hairy-related bHLH transcription factor family. HEY genes are candidates for several human or mouse disease loci.
Alias Symbols: HEY3, HRT3, bHLHb33
Protein Interaction Partner: RPGRIP1, RBPMS, MDFI, ZNF512B, HIPK3, LAPTM5, SKIL, ATXN1, PPP1CA, SMAD9, SMAD7, SMAD3, HTT, APP, UBC, SP8, ATF7IP, HAND2, HAND1,
Protein Size: 328

Molekulargewicht: 35 kDa

Gen-ID: 26508

NCBI Accession: NM_014571, NP_055386

UniProt: Q9NQ87

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling