ESRRG Antikörper (Middle Region)

Produktnummer ABIN2777400

Der Kaninchen Polyklonal Anti-ESRRG-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ESRRG in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für ESRRG Antikörper (Middle Region) (ABIN2777400)

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ESRRG Antikörper

Bindungsspezifität: Middle Region

Sequenz: RIDAENSPYL NPQLVQPAKK PYNKIVSHLL VAEPEKIYAM PDPTVPDSDI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ESRRG. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ESRRG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ESRRG Antikörper (ABIN2777400)

Song, Wang: "A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals." in: PLoS ONE, Vol. 4, Issue 11, pp. e7829, (2009) (PubMed).

Song, Wang: "Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma." in: Nucleic acids research, Vol. 36, Issue 18, pp. 5727-35, (2008) (PubMed).

Details zu ESRRG

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Andere Bezeichnung: ESRRG

Hintergrund: ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.
Alias Symbols: ERR3, NR3B3, ERRgamma
Protein Interaction Partner: MEOX2, KIFC3, ESRRG, NR0B1, SUMO1P1, CCDC67, KIAA1598, NUP160, SRPK1, SRA1, PPARGC1A, APP, PNRC2, NR0B2, TLE1, ESRRA, EIF3I, NRIP1, SRC, PROX1, DUT, ARHGEF15, PNRC1, EBP, UBC, PARK2, DPF2, SP1, PPARGC1B, DAXX, NCOA1, CALM1, HGS,
Protein Size: 458

Molekulargewicht: 51 kDa

Gen-ID: 2104

NCBI Accession: NM_206595, NP_996318

UniProt: P62508

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway