SLC26A3 Antikörper (Middle Region)

Produktnummer ABIN2777377

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC26A3 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen und Schaf.Es wurde in 1 Publikation zitiert.

Kurzübersicht für SLC26A3 Antikörper (Middle Region) (ABIN2777377)

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC26A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SLC26A3 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SLC26A3 Antibody - middle region

Sequenz: DAVLHILMKK DYSTSKFNPS QEKDGKIDFT INTNGGLRNR VYEVPVETKF

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC26A3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC26A3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31608-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC26A3 Antikörper (ABIN2777377)

Kjærgaard, Damm, Chang, Riis, Rasmussen, Hytting-Andreasen, Krug, Schulzke, Bindslev, Hansen: "Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?" in: International journal of molecular sciences, Vol. 21, Issue 5, (2020) (PubMed).

Details zu SLC26A3

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Andere Bezeichnung: SLC26A3

Hintergrund:

Background Information: SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Solute carrier family 26, member 3

Alternative Symbols: CLD, DRA

Protein Name: Chloride anion exchanger

Molekulargewicht: 84 kDa

Gen-ID: 1811

NCBI Accession: NP_000102

UniProt: P40879