TADA3L Antikörper (Middle Region)

Produktnummer ABIN2777322

Der Kaninchen Polyklonal anti-TADA3L Antikörper wird verwendet zum Nachweis von TADA3L in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für TADA3L Antikörper (Middle Region) (ABIN2777322)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TADA3L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TADA3L Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TADA3L Antibody - middle region

Sequenz: ASVEPYCADI TSEEVRTLEE LLKPPEDEAE HYKIPPLGKH YSQRWAQEDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TADA3L

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31479-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Andere Bezeichnung: TADA3L

Hintergrund:

Background Information: Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Gene Name: Transcriptional adaptor 3

Alternative Symbols: ADA3, NGG1, hADA3, STAF54, TADA3L

Protein Name: Transcriptional adapter 3

Molekulargewicht: 49kDa

Gen-ID: 10474

NCBI Accession: NP_006345

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway