AKAP8 Antikörper (Middle Region)

Produktnummer ABIN2777315

Der Kaninchen Polyklonal anti-AKAP8 Antikörper wird verwendet zum Nachweis von AKAP8 in Proben von Human, Ratte, Rind (Kuh), Hund, Pferd und Schwein. Er wurde validiert für WB.

Kurzübersicht für AKAP8 Antikörper (Middle Region) (ABIN2777315)

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKAP8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DVLAEVITAA VRAVDGEGAP APESSGEPAE DEGPTDTAEA GSDPQAEQLL

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against AKAP8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKAP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 692 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKAP8

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Andere Bezeichnung: AKAP8

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP8 is a member of the AKAP family. It is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AKAP95, DKFZp586B1222, AKAP-8, AKAP 95, AKAP-95
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, RNF2, EZH2, HIPK4, HDAC11, CSNK2A1, MYC, ESR1, BARD1, LRRK2, CAND1, COPS5, CUL3, HNRNPA1, ELAVL1, Mis12, Aurkb, TADA2A, CASP3, DDX5, PRKAR2A, CCND1, RELA, CCND3, CCND2, MCM2, AMY1C, AMY1A,
Protein Size: 692

Molekulargewicht: 76 kDa

Gen-ID: 10270

NCBI Accession: NM_005858, NP_005849

UniProt: O43823

Pathways: SARS-CoV-2 Protein Interaktom