OLIG2 Antikörper (N-Term)

Produktnummer ABIN2777314

Der Kaninchen Polyklonal Anti-OLIG2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, OLIG2 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Hund und Pferd zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für OLIG2 Antikörper (N-Term) (ABIN2777314)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-OLIG2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MDSDASLVSS RPSSPEPDDL FLPARSKGSS GSAFTGGTVS SSTPSDCPPE

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against OLIG2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OLIG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 323 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-OLIG2 Antikörper (ABIN2777314)

Mitkus, Hyde, Vakkalanka, Kolachana, Weinberger, Kleinman, Lipska: "Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia." in: Schizophrenia research, Vol. 98, Issue 1-3, pp. 129-38, (2007) (PubMed).

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: OLIG2

Hintergrund: OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14,21)(q11.2,q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Protein Interaction Partner: CUL3, SRRM1, SOX8, NKX2-2, EP300, SOX10,
Protein Size: 323

Molekulargewicht: 32 kDa

Gen-ID: 10215

NCBI Accession: NM_005806, NP_005797

UniProt: Q13516