HOXB5 Antikörper (N-Term)

Produktnummer ABIN2777303

Dieses Anti-HOXB5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOXB5 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für HOXB5 Antikörper (N-Term) (ABIN2777303)

Target: HOXB5 (Homeobox B5 (HOXB5))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HOXB5 Antikörper

Bindungsspezifität: N-Term

Sequenz: MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 269 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXB5 Antikörper (ABIN2777303)

Fu, Lui, Sham, Cheung, Tam: "HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 228, Issue 1, pp. 1-10, (2003) (PubMed).

Details zu HOXB5

Target: HOXB5 (Homeobox B5 (HOXB5))

Andere Bezeichnung: HOXB5

Hintergrund: HOXB5 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
Protein Size: 269

Molekulargewicht: 30 kDa

Gen-ID: 3215

NCBI Accession: NM_002147, NP_002138

UniProt: P09067