Msx2/Hox8 Antikörper (N-Term)

Produktnummer ABIN2777276

Der Kaninchen Polyklonal anti-Msx2/Hox8 Antikörper (ABIN2777276) detektiert spezifisch Msx2/Hox8 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für Msx2/Hox8 Antikörper (N-Term) (ABIN2777276)

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Msx2/Hox8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Msx2/Hox8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MSX2 Antibody - N-terminal region

Sequenz: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31398-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Msx2/Hox8

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Andere Bezeichnung: MSX2

Hintergrund:

Background Information: MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Msh homeobox 2

Alternative Symbols: FPP, MSH, PFM, CRS2, HOX8, PFM1

Protein Name: Homeobox protein MSX-2

Molekulargewicht: 29kDa

Gen-ID: 4488

NCBI Accession: NP_002440

UniProt: P35548