HOXD4 Antikörper (C-Term)

Produktnummer ABIN2777273

Dieses Anti-HOXD4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOXD4 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schwein und Pferd.

Kurzübersicht für HOXD4 Antikörper (C-Term) (ABIN2777273)

Target: HOXD4 (Homeobox D4 (HOXD4))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXD4 Antikörper

Bindungsspezifität: C-Term

Sequenz: RMKWKKDHKL PNTKGRSSSS SSSSSCSSSV APSQHLQPMA KDHHTDLTTL

Homologie: Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXD4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HOXD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 255 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HOXD4

Target: HOXD4 (Homeobox D4 (HOXD4))

Andere Bezeichnung: HOXD4

Hintergrund: HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
Alias Symbols: HOX4, HOX4B, HHO.C13, HOX-5.1, Hox-4.2
Protein Interaction Partner: EP300, CREBBP, TIGD4, ASB8, ZSCAN18, CNOT7, ZBTB32, RNPS1, ZMYND11, HOXB13, DEDD, SNAI1, RXRG, HNRNPAB, ETV4, PBX1, HIPK1, MEIS1, XRCC6,
Protein Size: 255

Molekulargewicht: 28 kDa

Gen-ID: 3233

NCBI Accession: NM_014621, NP_055436

UniProt: P09016