FOSL1 Antikörper (Middle Region)

Produktnummer ABIN2777265

Der Kaninchen Polyklonal Anti-FOSL1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, FOSL1 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Schaf zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für FOSL1 Antikörper (Middle Region) (ABIN2777265)

Target: FOSL1 (FOS-Like Antigen 1 (FOSL1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FOSL1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TDFLQAETDK LEDEKSGLQR EIEELQKQKE RLELVLEAHR PICKIPEGAK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 85%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FOSL1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOSL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 271 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOSL1 Antikörper (ABIN2777265)

Seitz, Schürmann, Pfeilschifter, Frank, Sader: "Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes." in: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, Vol. 40, Issue 4, pp. 379-86, (2012) (PubMed).

Kashiwada, Cassel, Colgan, Rothman: "NFIL3/E4BP4 controls type 2 T helper cell cytokine expression." in: The EMBO journal, Vol. 30, Issue 10, pp. 2071-82, (2011) (PubMed).

Details zu FOSL1

Target: FOSL1 (FOS-Like Antigen 1 (FOSL1))

Andere Bezeichnung: FOSL1

Hintergrund: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: FRA1, fra-1, FRA
Protein Interaction Partner: NME7, CREB5, USF1, LDOC1, JUNB, MAFB, MAF, JUN, DDIT3, ATF2, CEBPG, CEBPE, CEBPA, ATF4, ATF3, PARVG, WFDC1, TAB2, ATXN1, MYC, KPNA1, PSMC3, EP300, CREBBP, TRIM24, UBC, HDAC1, CALCOCO1, ATF1, CREB1, SRF, ELK1,
Protein Size: 271

Molekulargewicht: 29 kDa

Gen-ID: 8061

NCBI Accession: NM_005438, NP_005429

UniProt: P15407