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FOSL1 Antikörper (Middle Region)

This anti-FOSL1 antibody (ABIN2777265) is a Rabbit Polyclonal antibody detecting FOSL1 in WB, IHC. Suitable for Human, Rat, Mouse, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio), Sheep.
Produktnummer ABIN2777265

Kurzübersicht für FOSL1 Antikörper (Middle Region) (ABIN2777265)

Target

Alle FOSL1 Antikörper anzeigen
FOSL1 (FOS-Like Antigen 1 (FOSL1))

Reaktivität

  • 46
  • 32
  • 31
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schaf

Wirt

  • 45
  • 3
  • 2
Kaninchen

Klonalität

  • 48
  • 2
Polyklonal

Konjugat

  • 24
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FOSL1 Antikörper ist unkonjugiert

Applikation

  • 37
  • 15
  • 13
  • 13
  • 9
  • 7
  • 7
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    TDFLQAETDK LEDEKSGLQR EIEELQKQKE RLELVLEAHR PICKIPEGAK

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 85%, Zebrafish: 85%

    Produktmerkmale

    This is a rabbit polyclonal antibody against FOSL1. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human FOSL1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 271 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Seitz, Schürmann, Pfeilschifter, Frank, Sader: "Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes." in: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, Vol. 40, Issue 4, pp. 379-86, (2012) (PubMed).

    Kashiwada, Cassel, Colgan, Rothman: "NFIL3/E4BP4 controls type 2 T helper cell cytokine expression." in: The EMBO journal, Vol. 30, Issue 10, pp. 2071-82, (2011) (PubMed).

  • Target

    FOSL1 (FOS-Like Antigen 1 (FOSL1))

    Andere Bezeichnung

    FOSL1

    Hintergrund

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
    Alias Symbols: FRA1, fra-1, FRA
    Protein Interaction Partner: NME7, CREB5, USF1, LDOC1, JUNB, MAFB, MAF, JUN, DDIT3, ATF2, CEBPG, CEBPE, CEBPA, ATF4, ATF3, PARVG, WFDC1, TAB2, ATXN1, MYC, KPNA1, PSMC3, EP300, CREBBP, TRIM24, UBC, HDAC1, CALCOCO1, ATF1, CREB1, SRF, ELK1,
    Protein Size: 271

    Molekulargewicht

    29 kDa

    Gen-ID

    8061

    NCBI Accession

    NM_005438, NP_005429

    UniProt

    P15407
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