IRF8 Antikörper (C-Term)

Produktnummer ABIN2777225

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRF8 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schwein und wurde in 1 Publikation erwähnt.

Kurzübersicht für IRF8 Antikörper (C-Term) (ABIN2777225)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF8 Antikörper

Bindungsspezifität: C-Term

Sequenz: QLAEEAGKSC GAGSVMQAPE EPPPDQVFRM FPDICASHQR SFFRENQQIT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IRF8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 426 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-IRF8 Antikörper (ABIN2777225)

Ye, Wang, Wang, Wang, Song, Hou, Zhou, Li, Ho: "CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 3, pp. 753-62, (2009) (PubMed).

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8

Hintergrund: Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
Alias Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8
Protein Interaction Partner: SPI1, IRF1, TOP1, ZBTB17, PDGFRB, CBL, UBC, COPS4, COPS5, COPS6, COPS2, MID1, IRF6, GPS1, CDK4, SQSTM1, TRAF6, SMURF2, IRF2, TRIM21, IRF8, ETV6, RELA, NFKB1,
Protein Size: 426

Molekulargewicht: 48 kDa

Gen-ID: 3394

NCBI Accession: NM_002163, NP_002154

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin