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NFIL3 Antikörper (Middle Region)

Dieses Anti-NFIL3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NFIL3 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Kaninchen.
Produktnummer ABIN2777219

Kurzübersicht für NFIL3 Antikörper (Middle Region) (ABIN2777219)

Target

Alle NFIL3 Antikörper anzeigen
NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reaktivität

  • 38
  • 16
  • 16
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt

  • 36
  • 1
  • 1
Kaninchen

Klonalität

  • 38
Polyklonal

Konjugat

  • 26
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NFIL3 Antikörper ist unkonjugiert

Applikation

  • 31
  • 17
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

    Produktmerkmale

    This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 462 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

    Andere Bezeichnung

    NFIL3

    Hintergrund

    NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
    Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
    Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
    Protein Size: 462

    Molekulargewicht

    51 kDa

    Gen-ID

    4783

    NCBI Accession

    NM_005384, NP_005375

    UniProt

    Q16649
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