WT1 Antikörper (N-Term)

Produktnummer ABIN2777189

Dieses Anti-WT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WT1 in WB. Geeignet für Human, Ratte, Maus, Kaninchen, Hund, Schwein und Zebrafisch (Danio rerio).

Kurzübersicht für WT1 Antikörper (N-Term) (ABIN2777189)

Target: WT1 (Wilms Tumor 1 (WT1))

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: DFAPPGASAY GSLGGPAPPP APPPPPPPPP HSFIKQEPSW GGAEPHEEQC

Homologie: Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against WT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human WT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1

Hintergrund: WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRT40, EGR1, MDM2, DVL3, CIAO1, TP53, HSPA4, TAOK1, NPM3, ZNF205, SUZ12, MEN1, EZH2, DNMT1, WTIP, WTAP, PAWR, UBE2I, TP63, FHL2, TP73, PRKACA, CREBBP, U2AF2, PAX2, AREG,
Protein Size: 432

Molekulargewicht: 47 kDa

Gen-ID: 7490

Pathways: Tube Formation