ASCL1 Antikörper (N-Term)

Produktnummer ABIN2777176

Der Kaninchen Polyklonal Anti-ASCL1-Antikörper wurde für WB validiert. Er ist geeignet, ASCL1 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Hund und Kaninchen zu detektieren.

Kurzübersicht für ASCL1 Antikörper (N-Term) (ABIN2777176)

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ASCL1 Antikörper

Bindungsspezifität: N-Term

Sequenz: AQQQQQQQQQ QQQAPQLRPA ADGQPSGGGH KSAPKQVKRQ RSSSPELMRC

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ASCL1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ASCL1

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Andere Bezeichnung: ASCL1

Hintergrund: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
Protein Interaction Partner: MEF2D, MEF2C, MEF2A, NEUROG2, UBQLN1, EP300, TCF4, BMP2, ASCL1,
Protein Size: 236

Molekulargewicht: 25 kDa

Gen-ID: 429

NCBI Accession: NM_004316, NP_004307

UniProt: P50553

Pathways: Dopaminergic Neurogenesis