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PR (N-Term) Antikörper

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB validiert. Er ist geeignet, in Proben von Human, Ratte und Kaninchen zu detektieren.
Produktnummer ABIN2777173

Kurzübersicht für PR (N-Term) Antikörper (ABIN2777173)

Target

PR

Reaktivität

  • 7
  • 2
  • 2
  • 1
Human, Ratte, Kaninchen

Wirt

  • 5
  • 2
Kaninchen

Klonalität

  • 5
  • 2
Polyklonal

Konjugat

  • 7
Unkonjugiert

Applikation

  • 6
  • 6
  • 5
  • 5
Western Blotting (WB)
  • Bindungsspezifität

    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    LPRGLSPARQ LLLPASESPH WSGAPVKPSP QAAAVEVEEE DGSESEESAG

    Homologie

    Human: 100%, Rabbit: 91%, Rat: 91%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PR. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of human PGR
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PR

    Hintergrund

    This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
    Alias Symbols: PR, NR3C3
    Protein Size: 690

    Molekulargewicht

    75 kDa

    Gen-ID

    5241

    NCBI Accession

    NM_000926, NP_000917

    UniProt

    P06401
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