Cytokeratin 13 Antikörper (C-Term)

Produktnummer ABIN2777115

Dieses Anti-Cytokeratin 13-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cytokeratin 13 in WB und IHC. Geeignet für Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Pferd, Hund, Schwein, Schaf und Meerschweinchen.

Kurzübersicht für Cytokeratin 13 Antikörper (C-Term) (ABIN2777115)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Pferd, Hund, Schwein, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cytokeratin 13 Antikörper

Bindungsspezifität: C-Term

Sequenz: EAQLSELRSE MECQNQEYKM LLDIKTRLEQ EIATYRSLLE GQDAKKRQPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against KRT13. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT13

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 420 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Andere Bezeichnung: KRT13

Hintergrund: KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been described.
Alias Symbols: CK13, K13, MGC161462, MGC3781
Protein Interaction Partner: FAM127C, GOLGA8EP, KRT79, TRIM42, KRT6C, CEP57L1, TXLNA, PPP1R18, ALS2CR11, KLC3, C1orf216, CCDC101, KRT71, IFT20, KLC4, FBF1, ANKRD36BP1, LSM2, EXOSC5, C1orf109, CCHCR1, KRT20, AMOTL2, ABI3, BLOC1S6, FARS2, ABI2, CEP57, EIF4E2, TSG101, TMSB4X, PSMB2, PSM
Protein Size: 420

Molekulargewicht: 46 kDa

Gen-ID: 3860

NCBI Accession: NM_002274, NP_002265

UniProt: P13646