DLAT Antikörper (C-Term)
Kurzübersicht für DLAT Antikörper (C-Term) (ABIN2777102)
Target
Alle DLAT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- DLAT Antibody - C-terminal region
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Sequenz
- DVVSLATKAR EGKLQPHEFQ GGTFTISNLG MFGIKNFSAI INPPQACILA
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Homologie
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DLAT. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLAT
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41995-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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Andere Bezeichnung
- DLAT
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Hintergrund
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Background Information: DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AK057299.1 1-2696 2697-3933 BC039084.1 2066-3302 3934-4322 DB551427.1 98-486
Gene Name: Dihydrolipoamide S-acetyltransferase
Alternative Symbols: E2, PBC, DLTA, PDCE2, PDC-E2
Protein Name: Dihydrolipoamide S-acetyltransferase EMBL AAH39084.1
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Molekulargewicht
- 69kDa
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Gen-ID
- 1737
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NCBI Accession
- NP_001922
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UniProt
- Q86YI5
Target
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