ALOX15B Antikörper (C-Term)

Produktnummer ABIN310247

Produktdetails anti-ALOX15B Antikörper

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX15B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ATCEGFIATL PPVNATCDVI LALWLLSKEP GDQRPLGTYP DEHFTEEAPR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ALOX15B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALOX15B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 676 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALOX15B Antikörper (ABIN310247)

Subbarayan, Xu, Kim, Yang, Hoque, Sabichi, Llansa, Mendoza, Logothetis, Newman, Lippman, Menter: "Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia." in: Neoplasia (New York, N.Y.), Vol. 7, Issue 3, pp. 280-93, (2005) (PubMed).

Details zu ALOX15B

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Andere Bezeichnung: ALOX15B (ALOX15B Produkte)

Hintergrund: ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: 15-LOX-2
Protein Interaction Partner: RXRA, PPARG, ERAL1,
Protein Size: 676

Molekulargewicht: 74 kDa

Gen-ID: 247

NCBI Accession: NM_001141, NP_001132

UniProt: O15296