TSH receptor Antikörper (C-Term)

Produktnummer ABIN2777037

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TSH receptor in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Kaninchen, Schaf, Rind (Kuh), Pferd und Meerschweinchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für TSH receptor Antikörper (C-Term) (ABIN2777037)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Schaf, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TSH receptor Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TSHR Antibody - C-terminal region

Sequenz: KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS

Homologie: Cow: 83%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TSHR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TSHR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113889

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TSH receptor Antikörper (ABIN2777037)

Pessina, Castillo, Sartore, Borrego, Meikle: "Semiquantitative immunohistochemical marker staining and localization in canine thyroid carcinoma and normal thyroid gland." in: Veterinary and comparative oncology, (2014) (PubMed).

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR

Hintergrund:

Background Information: TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).

Gene Name: Thyroid stimulating hormone receptor

Alternative Symbols: LGR3, CHNG1, hTSHR-I

Protein Name: Thyrotropin receptor

Molekulargewicht: 87 kDa

Gen-ID: 7253

NCBI Accession: NP_001018046

UniProt: Q96GT6

Pathways: Thyroid Hormone Synthesis