TSH receptor Antikörper (N-Term)

Produktnummer ABIN2777036

Der Kaninchen Polyklonal anti-TSH receptor Antikörper (ABIN2777036) detektiert spezifisch TSH receptor in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Kaninchen, Schaf, Rind (Kuh) und Pferd.

Kurzübersicht für TSH receptor Antikörper (N-Term) (ABIN2777036)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Schaf, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TSH receptor Antikörper

Bindungsspezifität: N-Term

Sequenz: CHQEEDFRVT CKDIQRIPSL PPSTQTLKLI ETHLRTIPSH AFSNLPNISR

Homologie: Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 77%, Rat: 79%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TSHR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TSHR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 253 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR

Hintergrund: TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
Alias Symbols: LGR3, MGC75129, hTSHR-I, CHNG1
Protein Interaction Partner: ADRB2, SCRIB, UBC, TSHB, RABAC1, GNA13, GNA12, FLNB, TSHR, GNAQ, PIK3R1, LHCGR, JAK2, JAK1, GNAI3, GNAI2, GNAS, GNA11, GNAO1, GNAI1, HSPA5, FN1, CANX, CALR, STAT3, CALCR,
Protein Size: 253

Molekulargewicht: 28 kDa

Gen-ID: 7253

NCBI Accession: NM_001018036, NP_001018046

UniProt: Q96GT6

Pathways: Thyroid Hormone Synthesis