GHRHR Antikörper (C-Term)

Produktnummer ABIN2777029

Der Kaninchen Polyklonal anti-GHRHR Antikörper (ABIN2777029) detektiert spezifisch GHRHR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Schwein, Rind (Kuh), Schaf, Hund, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für GHRHR Antikörper (C-Term) (ABIN2777029)

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Schaf, Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GHRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GHRHR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: GHRHR Antibody - C-terminal region

Sequenz: YWWIIKGPIV LSVGVNFGLF LNIIRILVRK LEPAQGSLHT QSQYWYCVFV

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 91%, Rat: 83%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GHRHR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GHRHR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41859-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GHRHR

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Andere Bezeichnung: GHRHR

Hintergrund:

Background Information: GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.

Gene Name: Growth hormone releasing hormone receptor

Alternative Symbols: GRFR, GHRFR, IGHD4, IGHD1B

Molekulargewicht: 37kDa

Gen-ID: 2692

NCBI Accession: NP_001009824

UniProt: Q02643

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process