BDKRB2 Antikörper (N-Term)

Produktnummer ABIN2776988

Der Kaninchen Polyklonal Anti-BDKRB2-Antikörper wurde für WB validiert. Er ist geeignet, BDKRB2 in Proben von Human und Rind (Kuh) zu detektieren.

Kurzübersicht für BDKRB2 Antikörper (N-Term) (ABIN2776988)

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BDKRB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BDKRB2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MFSPWKISMF LSVREDSVPT TASFSADMLN VTLQGPTLNG TFAQSKCPQV

Homologie: Cow: 77%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BDKRB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BDKRB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 391 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BDKRB2

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Andere Bezeichnung: BDKRB2

Hintergrund: BDKRB2 is a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system.This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
Alias Symbols: B2R, BK-2, BK2, BKR2, BRB2, DKFZp686O088
Protein Interaction Partner: BAG3, ACE, GRK5, GRK6, PRKCD, PTPN11, NOS1, NOS3, GNA11, GRK4, ADRBK2, ADRBK1, AGTR1,
Protein Size: 391

Molekulargewicht: 43 kDa

Gen-ID: 624

NCBI Accession: NM_000623, NP_000614

UniProt: P30411

Pathways: ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling