Keratin 2 Antikörper (Middle Region)

Produktnummer ABIN2776963

Der Kaninchen Polyklonal Anti-Keratin 2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Keratin 2 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein und Kaninchen zu detektieren.

Kurzübersicht für Keratin 2 Antikörper (Middle Region) (ABIN2776963)

Target: Keratin 2 (KRT2)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Keratin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Keratin 2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EVKAQYEEIA QRSKEEAEAL YHSKYEELQV TVGRHGDSLK EIKIEISELN

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 81%

Produktmerkmale: This is a rabbit polyclonal antibody against KRT2A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 639 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Keratin 2

Target: Keratin 2 (KRT2)

Andere Bezeichnung: KRT2A

Hintergrund: KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: KRT2E, KRTE, K2e, CK-2e, KRT2A
Protein Interaction Partner: KRT40, KRT38, KRT31, KRT19, KRT13, Fbxl16, LGR4, EED, ADRB2, PAN2, Nphp4, IQCB1, VCAM1, UBC, FN1, EIF4A3, MAGOH, KRT10, KRT1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5,
Protein Size: 639

Molekulargewicht: 70 kDa

Gen-ID: 3849

NCBI Accession: NM_000423, NP_000414

UniProt: P35908