Amylin/DAP Antikörper (N-Term)

Produktnummer ABIN2776959

Der Kaninchen Polyklonal anti-Amylin/DAP Antikörper (ABIN2776959) detektiert spezifisch Amylin/DAP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Kaninchen, Hund, Rind (Kuh) und Pferd.

Kurzübersicht für Amylin/DAP Antikörper (N-Term) (ABIN2776959)

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reaktivität: Human, Kaninchen, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amylin/DAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Amylin/DAP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IAPP Antibody - N-terminal region

Sequenz: MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV

Homologie: Cow: 82%, Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IAPP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IAPP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41728-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Andere Bezeichnung: IAPP

Hintergrund:

Background Information: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Gene Name: Islet amyloid polypeptide

Alternative Symbols: DAP, IAP

Protein Name: Islet amyloid polypeptide

Molekulargewicht: 4kDa

Gen-ID: 3375

NCBI Accession: NP_000406

UniProt: P10997

Pathways: Hormone Activity, Feeding Behaviour