Cardiac Troponin T2 Antikörper (N-Term)

Produktnummer ABIN2776953

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Cardiac Troponin T2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für Cardiac Troponin T2 Antikörper (N-Term) (ABIN2776953)

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cardiac Troponin T2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cardiac Troponin T2 Antikörper

Bindungsspezifität: N-Term

Sequenz: ESKPKPRSFM PNLVPPKIPD GERVDFDDIH RKRMEKDLNE LQALIEAHFE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNNT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Andere Bezeichnung: TNNT2

Hintergrund: TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Alias Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6
Protein Interaction Partner: MORF4L2, KDM1A, APP, TNNI1, TNNC1, UBC, TNNI3, MAP3K5, TPM1, PRKCA,
Protein Size: 295

Molekulargewicht: 35 kDa

Gen-ID: 7139

NCBI Accession: NM_000364, NP_000355

UniProt: A2TDB9