GAMT Antikörper (N-Term)

Produktnummer ABIN2776937

Der Kaninchen Polyklonal anti-GAMT Antikörper (ABIN2776937) detektiert spezifisch GAMT in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Meerschweinchen, Rind (Kuh) und Schwein.

Kurzübersicht für GAMT Antikörper (N-Term) (ABIN2776937)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GAMT Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GAMT Antibody - N-terminal region

Sequenz: MSAPSATPIF APGENCSPAW GAAPAAYDAA DTHLRILGKP VMERWETPYM

Homologie: Cow: 92%, Guinea Pig: 85%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GAMT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102022

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Andere Bezeichnung: GAMT

Hintergrund:

Background Information: GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.

Gene Name: Guanidinoacetate N-methyltransferase

Alternative Symbols: PIG2, CCDS2, TP53I2, HEL-S-20

Protein Name: Guanidinoacetate N-methyltransferase

Molekulargewicht: 26kDa

Gen-ID: 2593

NCBI Accession: NP_000147

UniProt: Q14353