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ALAD Antikörper (N-Term)

Dieses Anti-ALAD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALAD in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae.
Produktnummer ABIN2776920

Kurzübersicht für ALAD Antikörper (N-Term) (ABIN2776920)

Target

Alle ALAD Antikörper anzeigen
ALAD (Aminolevulinate Dehydratase (ALAD))

Reaktivität

  • 26
  • 19
  • 8
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt

  • 39
  • 7
Kaninchen

Klonalität

  • 42
  • 4
Polyklonal

Konjugat

  • 32
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ALAD Antikörper ist unkonjugiert

Applikation

  • 44
  • 14
  • 13
  • 13
  • 10
  • 8
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    QPQSVLHSGY FHPLLRAWQT ATTTLNASNL IYPIFVTDVP DDIQPITSLP

    Homologie

    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 77%, Zebrafish: 83%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ALAD. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human ALAD
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 339 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ALAD (Aminolevulinate Dehydratase (ALAD))

    Andere Bezeichnung

    ALAD

    Hintergrund

    The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ALADH, MGC5057, PBGS
    Protein Interaction Partner: C14orf142, P3H1, RPRD1B, PPME1, LAP3, DBNL, HSPBP1, GPN1, WDR4, ACTR2, TOM1L1, ZPR1, OGT, SURF2, LPP, AGFG1, UBD, UBC, ALAD,
    Protein Size: 339

    Molekulargewicht

    37 kDa

    Gen-ID

    210

    NCBI Accession

    NM_000031, NP_000022

    UniProt

    P13716
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