GPX3 Antikörper (N-Term)

Produktnummer ABIN2776848

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GPX3 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Schwein, Rind (Kuh) und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für GPX3 Antikörper (N-Term) (ABIN2776848)

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GPX3 Antikörper

Bindungsspezifität: N-Term

Sequenz: DCHGGISGTI YEYGALTIDG EEYIPFKQYA GKYVLFVNVA SYUGLTGQYI

Homologie: Cow: 100%, Dog: 83%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GPX3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPX3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 226 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GPX3 Antikörper (ABIN2776848)

Maccarrone, Ditzen, Yassouridis, Rewerts, Uhr, Uhlen, Holsboer, Turck: "Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters." in: Journal of psychiatric research, Vol. 47, Issue 11, pp. 1572-80, (2013) (PubMed).

Details zu GPX3

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Andere Bezeichnung: GPX3

Hintergrund: GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
Alias Symbols: GPx-P, GSHPx-3, GSHPx-P
Protein Interaction Partner: UBQLN1, GPX3,
Protein Size: 226

Molekulargewicht: 25 kDa

Gen-ID: 2878

NCBI Accession: NM_002084, NP_002075

UniProt: P22352

Pathways: Thyroid Hormone Synthesis