Desmin Antikörper (N-Term)

Produktnummer ABIN2776842

Der Kaninchen Polyklonal anti-Desmin Antikörper wird verwendet zum Nachweis von Desmin in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für Desmin Antikörper (N-Term) (ABIN2776842)

Target: Desmin (DES)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Desmin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DES Antibody - N-terminal region

Sequenz: PLSSPVFPRA GFGSKGSSSS VTSRVYQVSR TSGGAGGLGS LRASRLGTTR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DES. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DES

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41482-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: DES

Hintergrund:

Background Information: DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Gene Name: Desmin

Alternative Symbols: CSM1, CSM2, CDCD3, LGMD1D, LGMD1E, LGMD2R

Protein Name: Desmin

Molekulargewicht: 52kDa

Gen-ID: 1674

NCBI Accession: NP_001918

UniProt: P17661