DPYS Antikörper (N-Term)

Produktnummer ABIN2776832

Der Kaninchen Polyklonal Anti-DPYS-Antikörper wurde für WB validiert. Er ist geeignet, DPYS in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen und Schwein zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für DPYS Antikörper (N-Term) (ABIN2776832)

Target: DPYS (Dihydropyrimidinase (DPYS))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DPYS Antikörper

Bindungsspezifität: N-Term

Sequenz: VLDAAGKLVL PGGIDTHTHM QFPFMGSRSI DDFHQGTKAA LSGGTTMIID

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against DPYS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DPYS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 519 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DPYS Antikörper (ABIN2776832)

Thomas, Chen, Lin, Tomlinson, Lam, Liu, Yeung, Chan, Wong: "Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients." in: Cerebrovascular diseases (Basel, Switzerland), Vol. 25, Issue 3, pp. 261-7, (2008) (PubMed).

Thomas, Ezzeldin, Guarcello, Mattison, Fridley, Diasio: "Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism." in: Pharmacogenetics and genomics, Vol. 18, Issue 1, pp. 25-35, (2008) (PubMed).

Details zu DPYS

Target: DPYS (Dihydropyrimidinase (DPYS))

Andere Bezeichnung: DPYS

Hintergrund: Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Alias Symbols: DHP, DHPase
Protein Interaction Partner: DPYSL5,
Protein Size: 519

Molekulargewicht: 56 kDa

Gen-ID: 1807

NCBI Accession: NM_001385, NP_001376

UniProt: Q14117