SLC13A3 Antikörper (Middle Region)
Kurzübersicht für SLC13A3 Antikörper (Middle Region) (ABIN2776815)
Target
Alle SLC13A3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- SLC13A3 Antibody - middle region
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Sequenz
- GLSFRGWRKN KSEIRTNAED RARAVIREEY QNLGPIKFAE QAVFILFCMF
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Homologie
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 85%, Rabbit: 93%, Rat: 92%, Zebrafish: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SLC13A3. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SLC13A3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112059
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))
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Andere Bezeichnung
- SLC13A3
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Hintergrund
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Background Information: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
Gene Name: Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Alternative Symbols: NADC3, SDCT2, ARLIAK
Protein Name: Solute carrier family 13 member 3
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Molekulargewicht
- 61kDa
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Gen-ID
- 64849
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NCBI Accession
- NP_001011554
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UniProt
- Q8WWT9
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Pathways
- Dicarboxylic Acid Transport
Target
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