DDC Antikörper (N-Term)
Kurzübersicht für DDC Antikörper (N-Term) (ABIN2776802)
Target
Alle DDC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- EFRRRGKEMV DYVANYMEGI EGRQVYPDVE PGYLRPLIPA AAPQEPDTFE
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Homologie
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 92%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DDC. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DDC
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 480 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." in: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).
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: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." in: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).
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- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
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Andere Bezeichnung
- DDC
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Hintergrund
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DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Alias Symbols: AADC
Protein Interaction Partner: ATF6, RELA, AR,
Protein Size: 480 -
Molekulargewicht
- 53 kDa
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Gen-ID
- 1644
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NCBI Accession
- NM_000790, NP_000781
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UniProt
- P20711
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Pathways
- Dopaminergic Neurogenesis
Target
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