HRG Antikörper (Middle Region)

Produktnummer ABIN2776784

Produktdetails anti-HRG Antikörper

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Bindungsspezifität: Middle Region

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EVLPLPEANF PSFPLPHHKH PLKPDNQPFP QSVSESCPGK FKSGFPQVSM

Homologie: Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HRG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HRG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 525 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HRG

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Andere Bezeichnung: HRG (HRG Produkte)

Synonyme: AI265597 antikoerper, AW413091 antikoerper, D16jh2 antikoerper, D18020 antikoerper, Hprg antikoerper, Hrgp antikoerper, HPRG antikoerper, HRGP antikoerper, THPH11 antikoerper, HRG1 antikoerper, histidine rich glycoprotein antikoerper, histidine-rich glycoprotein antikoerper, HRG antikoerper, LOAG_12427 antikoerper, LOC100597044 antikoerper, Hrg antikoerper

Hintergrund: This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp779H1622, HPRG, HRGP
Protein Interaction Partner: RCHY1, RABAC1, SPRY1, CHRD, TNFRSF1A, PLSCR1, FN1, THBS1, PLG, FCGR1A, FGA, C1QB, C1QA,
Protein Size: 525

Molekulargewicht: 60 kDa

Gen-ID: 3273

NCBI Accession: NM_000412, NP_000403

UniProt: P04196