TNNI3 Antikörper (Middle Region)

Produktnummer ABIN2776782

Dieses Anti-TNNI3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TNNI3 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Ziege, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für TNNI3 Antikörper (Middle Region) (ABIN2776782)

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Ziege, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TNNI3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RVRISADAMM QALLGARAKE SLDLRAHLKQ VKKEDTEKEN REVGDWRKNI

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TNNI3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNNI3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 210 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: TNNI3

Hintergrund: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 is the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMH7, MGC116817, TNNC1, cTnI, RCM1, CMD2A, CMD1FF
Protein Interaction Partner: TNNC2, TRIM63, TRIM55, RCAN3, TNNC1, TNNI3K, PKD2L1, TNNI3, TNNT2, TNNT1, PRKCA, PAPPA, PKD2, ACTA1, LYST,
Protein Size: 210

Molekulargewicht: 23 kDa

Gen-ID: 7137

NCBI Accession: NM_000363, NP_000354

UniProt: Q59H18