PTH1R Antikörper (N-Term)
Kurzübersicht für PTH1R Antikörper (N-Term) (ABIN2776779)
Target
Alle PTH1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- ARIAPGLALL LCCPVLSSAY ALVDADDVMT KEEQIFLLHR AQAQCEKRLK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PTH1R. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human PTH1R
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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Andere Bezeichnung
- PTH1R
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Hintergrund
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The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: PFE, PTHR, PTHR1
Protein Size: 333 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 5745
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NCBI Accession
- NM_000316, NP_000307
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UniProt
- Q03431
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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