PTH1R Antikörper (N-Term)

Produktnummer ABIN2776779

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PTH1R in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Schwein, Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für PTH1R Antikörper (N-Term) (ABIN2776779)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PTH1R Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PTH1R Antibody - N-terminal region

Sequenz: ARIAPGLALL LCCPVLSSAY ALVDADDVMT KEEQIFLLHR AQAQCEKRLK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTH1R. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PTH1R

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41385-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: PTH1R

Hintergrund:

Background Information: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: parathyroid hormone 1 receptor

Alternative Symbols: PFE, EKNS, PTHR, PTHR1

Protein Name: parathyroid hormone/parathyroid hormone-related peptide receptor

Molekulargewicht: 36kDa

Gen-ID: 5745

NCBI Accession: NP_000307

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process